Anti-Human FGFR1 Recombinant Antibody (FR1-H7) (CAT#: TAB-052WM)
Antibody FR1-H7 binds FGFR-1(IIIb) and -1(IIIc) with strong affinities, but does not recognize any of the other FGFRs. Results from kinetic analysis indicated the antibody binds to FGFR-1b and -1c equally well. The KDs of the interactions were determined to be approximately 50 μM for both receptors. This product can be potentially used for antagonizing EGFR-1 or EGFR-4 as a treatment for obesity, diabetes, or a condition related thereto, and methods of reducing food intake.
Specific Inquiry
WB
Figure 1 Anti-FGFR1 Therapeutic Antibody (FR1-H7) (TAB-052WM) in Western Blot
WB analysis of TAB-052WM (left) and negative control (no TAB-052WM incubation, right)
Lane 1: Non-reducing condition
Lane 2: Reducing condition
Antigen: Recombinant Human FGFR1 Protein (His Tag)
ELISA
Figure 2 Anti-FGFR1 Therapeutic Antibody (FR1-H7) (TAB-052WM) in ELISA
ELISA analysis of TAB-052WM was performed by coating with Recombinant Human FGFR1 Protein (His Tag).
Specifications
- Host Species
- Human
- Derivation
- Phage-displayed human Fab library
- Type
- Human Antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- FR1-H7
- Applications
- ELISA, Neut
- Related Disease
- Obesity, diabetes
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Neutralization. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- FGFR1; fibroblast growth factor receptor 1; CEK; FLG; HH2; OGD; FLT2; KAL2; BFGFR; CD331; FGFBR; FLT-2; HBGFR; N-SAM; FGFR-1; HRTFDS; bFGF-R-1; FGFR1/PLAG1 fusion; proto-oncogene c-Fgr; FMS-like tyrosine kinase 2; hydroxyaryl-protein kinase; fms-related tyrosine kinase 2; heparin-binding growth factor receptor; basic fibroblast growth factor receptor 1
- Gene ID
- 2260
- UniProt ID
- P11362
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-283CL | Human Anti-FGFR1 Recombinant Antibody (TAB-283CL) | WB, IHC | Human IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Adaptable apps
This antibody exhibits exceptional adaptability and maintains performance quality across a variety of assays.
Perfect for targets with low abundance
Low-abundance proteins in samples were successfully identified. This antibody's sensitivity has changed the game.
Improved blocking efficiency
When blocking steps were completed correctly, the antibody produced clear findings. efficient against background problems in different experimental configurations.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-052WM, RRID: AB_3111778)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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